![]() Immunity and antioxidant capacity in humans is enhanced by consumption of a dried, encapsulated fruit and vegetable juice concentrate. Nantz MP, Rowe CA, Nieves C, Jr., Pervical SS.Several indicators of oxidative stress, immunity, and illness improved in trained men consuming an encapsulated juice powder concentrate for 28 weeks. Lamprecht M, Oettl K, Schwaberger G, et al.Juice Powder Concentrate and Systemic Blood Pressure, Progression of Coronary Artery Calcium and Antioxidant Status in Hypertensive Subjects: A Pilot Study. Houston MC, Cooil B, Olafsson BJ, Raggi P.Effect of supplemental phytonutrients on impairment of the flow-mediated brachial artery vasoactivity after a single high-fat meal. Plotnick GD, Corretti MC, Vogel RA, et al.Oxidative stress response to aerobic exercise: comparison of antioxidant supplements. Four week supplementation with mixed fruit and vegetable juice concentrates increased protective serum antioxidants and folate and decreased plasma homocysteine in Japanese subjects. ![]() Kawashima A, Madarame T, Koike H, et al.A mixed fruit and vegetable concentrate increases plasma antioxidant vitamins and folate and lowers plasma homocysteine in men. Samman S, Sivarajah G, Man JC, Ahmad ZI, Petocz P, Caterson ID.JP is not a substitute for fresh fruits and vegetables. Cancer patients should discuss the use of supplements with their physicians. Due to its antioxidant effects, JP may interfere with the actions of some chemotherapy drugs. While there is ongoing research using JP in cancer patients, it has not been proven to prevent or treat cancers. In a study of head and neck cancer patients, JP appeared to increase serum micronutrient levels, but provided no clinical benefit (15). Gastrointestinal distress (5) and hive-like rash (11) have been associated with intake of JP in clinical trials. JP is thought to reduce oxidative stress and DNA damage (2) (6) (10), and has been associated with a reduction in common cold symptoms (12). Other studies on cardiovascular effects such as changes in blood pressure and cholesterol levels were inconclusive (4) (5). Although JP appeared to decrease plasma homocysteine levels, a risk factor for cardiovascular disease (1) (9), the results were not reproducible (4). JP was comparable to standard vitamin C and E supplements (3), but it remains unclear if this product is nutritionally superior to fresh produce. Studies on bioavailability suggest that consumption of JP can increase serum levels of alpha-carotene, vitamin C, and folate (1) (2), but studies with other markers such as lutein and alpha-tocopherol yielded mixed results. It is marketed to complement the daily diet based on the notion that people do not consume enough fruits and vegetables. Juice Plus (JP) is a formulation derived from a variety of fruits and vegetables that contains additional vitamins. In using this website you agree that neither Memorial Sloan Kettering nor any other party is or will be liable or otherwise responsible for any decision made or any action taken or any action not taken due to your use of any information presented at this website. You are hereby advised to consult with a physician or other professional health-care provider prior to making any decisions, or undertaking any actions or not undertaking any actions related to any health care problem or issue you might have at any time, now or in the future. Memorial Sloan Kettering does not record specific website user information and does not contact users of this website. Use of this Web site does not create an expressed or implied physician-patient relationship. Statements made about products have not been evaluated by the Food and Drug Administration. Health-related information changes frequently and therefore information contained on this Web site may be outdated, incomplete or incorrect. Memorial Sloan Kettering does not assume any risk whatsoever for your use of this website or the information contained herein. Memorial Sloan Kettering Cancer Center makes no warranties nor express or implied representations whatsoever regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced on this Web site. Any questions regarding your own health should be addressed to your own physician or other healthcare provider. Users of this Web site should not rely on information provided on this Web site for their own health problems. This Web site is not to be used as a substitute for medical advice, diagnosis or treatment of any health condition or problem. This Web site - Information About Herbs, Botanicals and Other Products - is for general health information only.
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